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1.
Front Public Health ; 11: 1208751, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38045981

RESUMO

Background: In November 2019, an infectious agent that caused a severe acute respiratory illness was first detected in China. Its rapid spread resulted in a global lockdown with negative economic impacts. In this regard, we expose the solutions proposed by a multinational financial institution that maintained their workers on premises, so this methodology can be applied to possible future health crisis. Objectives: To ensure a secure workplace for the personnel on premises employing biomedical prevention measures and computational tools. Methods: Professionals were subjected to recurrent COVID-19 diagnostic tests during the pandemic. The sanitary team implemented an individual following to all personnel and introduced the information in databases. The data collected were used for clustering algorithms, decision trees, and networking diagrams to predict outbreaks in the workplace. Individualized control panels assisted the decision-making process to increase, maintain, or relax restrictive measures. Results: 55,789 diagnostic tests were performed. A positive correlation was observed between the cumulative incidence reported by Madrid's Ministry of Health and the headcount. No correlation was observed for occupational infections, representing 1.9% of the total positives. An overall 1.7% of the cases continued testing positive for COVID-19 after 14 days of quarantine. Conclusion: Based on a combined approach of medical and computational science tools, we propose a management model that can be extended to other industries that can be applied to possible future health crises. This work shows that this model resulted in a safe workplace with a low probability of infection among workers during the pandemic.


Assuntos
COVID-19 , Pandemias , Humanos , Pandemias/prevenção & controle , COVID-19/epidemiologia , Local de Trabalho , Quarentena , Computadores
3.
J Occup Environ Med ; 63(10): 895-900, 2021 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-33973932

RESUMO

OBJECTIVES: In addition to personal and health related factors, healthcare workers have an increased risk due to their work. We assessed the association of the score of the Occupational Vulnerability Index with the risk of suffering a severe COVID-19 and sequelae. METHODS: Retrospective observational study carried out in healthcare workers. Among 119 employees infected, the COVID-19 Occupational Vulnerability Index (composed of 29 items regarding personal health, working conditions, and ability to comply with preventive measures) was calculated and correlated with COVID-19 severity/sequelae. RESULTS: Workers with higher scores (six to seven points) had a significantly increased risk of developing severe disease (OR = 9.73; 95% CI, 1.53 to 35.56) and clinical sequelae (OR = 5.22; 95% CI, 1.80 to 15.16) than those with lower scores (0 to 3). CONCLUSION: The "COVID-19 Occupational Vulnerability Index" may predict the risk of severe COVID-19 disease and clinical sequelae among healthcare workers.


Assuntos
COVID-19 , Pessoal de Saúde , Hospitais , Humanos , Recursos Humanos em Hospital , Estudos Retrospectivos , SARS-CoV-2
4.
Arch. med ; 21(2): 492-502, 2021-04-25.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1291824

RESUMO

Objetivo: valorar el uso de terapias alternativas no farmacológicas en migraña y variables relacionadas. La migraña afecta a una de cada diez personas en el mundo, con aumento creciente y mayor prevalencia entre mujeres de zonas urbanas. Aunque los tratamientos habituales son farmacológicos, se ha incrementado el uso de terapias alternativas no farmacológicas en migraña y variables relacionadas. Materiales y métodos: estudio observacional transversal mediante encuesta anónima vía web a 3.342 pacientes de países europeos sobre el uso de terapias alternativas para tratamiento de migraña. Variables de estudio: edad, género, país, tipo de localidad, nivel de estudios, ámbito rural o urbano y respuesta al tratamiento. Resultados: la utilización de terapias alternativas en migraña es un fenómeno creciente, con mayor uso en pacientes entre 41-60 años y estudios superiores. Conclusiones: en migraña se observan diferencias por edad, género, nivel cultural y país de procedencia. El uso de la medicina complementaria como alternativa terapéutica en la migraña es poco habitual y se debería indagar con mayor profundidad estableciendo relaciones que permitan apoyar al paciente afectado y priorizar las de mayor evidencia científica..(Au)


Objective: to evaluate the use of alternative non-pharmacological therapies in migraine and related variables. Migraine affects one in ten people worldwide, with a growing increase and a higher prevalence among women in urban areas. Although the usual treatments are pharmacological, the use of alternative techniques is increasing. Materials and methods: cross-sectional observational study by anonymous web survey of 3,342 patients from European countries on the use of alternative therapies. Study variables: age, gender, country, type of locality, educational level, rural or urban setting and treatment response. Results: the use of alternative therapies in migraine treatment is a growing phenomenon, with greater use in patients between 41-60 years of age and higher education. Conclusions: in Migraine, differences are observed by age, gender, cultural level and country of origin. The use of complementary medicine as an therapeutic alternative in migraine is uncommon and should be investigated in greater depth, establishing relationships that allow supporting the affected patient and prioritizing, if possible, some over others with scientific evidence..(Au)

5.
Arch Prev Riesgos Labor ; 24(1): 20-33, 2021 01 21.
Artigo em Espanhol | MEDLINE | ID: mdl-33691037

RESUMO

INTRODUCTION: Workplace health promotion integrates initiatives in health and safety in the occupational field, with personal improvements, increased productivity and lower risks and social cost, especially with respect to migraine headaches, a neurological disorder affecting approximately 11% of the population. The objective of this study was to know the preventive resources available to workers with migraine headaches and the preventive management options in their companies. METHOD: Cross-sectional observational study of 3,342 patients from Spain, Italy, France, Portugal, Ireland, United Kingdom, Germany and other European Union countries, conducted through an anonymous survey on the web of the European Migraine & Headache Alliance (EMHA-web), from September 2018 to January 2019. RESULTS: Occupational stress (77.65%) and use of computer monitors (63.87%) are the most common risks described by workers with migraine. About. 43.71% of workers are not familiar with the type of occupational health service present in their company, 49.06% do not have a medical service; 67.67% reported no work-related limitations due to migraine, neither dismissal nor non-renewal of their contract (88.29%), but 42.14% had experienced some conflict due to decreased productivity; 26.54% were unaware of the concept of vulnerable workers or had not requested this status because of their migraine (63.8%), nor had.


INTRODUCCIÓN: La promoción de la salud en el trabajo integra las iniciativas en salud y seguridad en ámbito ocupacional, con mejoras personales, incremento de productividad y menores riesgos y gastos sociales, especialmente en migraña, como enfermedad neurológica con prevalencia estimada en el 11% de la población. El objetivo de este trabajo fue conocer las condiciones preventivas de los trabajadores con migraña y las opciones de gestión preventiva en sus empresas. MÉTODO: Estudio observacional transversal realizado en 3.342 pacientes de España, Italia, Francia, Portugal, Irlanda, Reino Unido, Alemania y otros países de la UE mediante encuesta anónima en la web de la European Migraine & Headache Alliance(EMHA-web), entre septiembre de 2018 y enero de 2019.RESULTADOS: Estrés laboral (77.65%) y uso de PVD (63.87%) son los riesgos más referidos por los trabajadores con migraña. El 43.71% de trabajadores desconoce el tipo de Servicio de Prevención de su empresa, 49.06% no dispone de servicio médico; el 67.67% no ha tenido impedimentos de acceso laboral por migraña, ni despido o no renovación del contrato (88,29%), pero el 42,14% tuvo algún conflicto por pérdida de productividad; el 26,54% desconoce el concepto de especial sensibilidad o no lo ha solicitado por migraña (63,8%), ni ha demandado modificaciones laborales (67,64%) o cambio de puesto de trabajo (80,89%); un 55,42% no se ha sentido comprendido ni apoyado por su empresa en sus limitaciones por migraña, pero sí por los compañeros (63,07%). CONCLUSIÓN:Se observa una deficiente información preventiva y escaso uso de las opciones de gestión adaptativa en las empresas para personas con migraña.


Assuntos
Transtornos de Enxaqueca , Estudos Transversais , França , Alemanha , Humanos , Irlanda , Itália , Transtornos de Enxaqueca/epidemiologia , Transtornos de Enxaqueca/prevenção & controle , Portugal , Espanha , Reino Unido , Local de Trabalho
6.
Rev Esp Cardiol (Engl Ed) ; 74(5): 438-448, 2021 May.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-33712348

RESUMO

Both cancer treatment and survival have significantly improved, but these advances have highlighted the deleterious effects of vascular complications associated with anticancer therapy. This consensus document aims to provide a coordinated, multidisciplinary and practical approach to the stratification, monitoring and treatment of cardiovascular risk in cancer patients. The document is promoted by the Working Group on Cardio Oncology of the Spanish Society of Cardiology (SEC) and was drafted in collaboration with experts from distinct areas of expertise of the SEC and the Spanish Society of Hematology and Hemotherapy (SEHH), the Spanish Society of Medical Oncology (SEOM), the Spanish Society of Radiation Oncology (SEOR), the Spanish Society of General and Family Physicians (SEMG), the Spanish Association of Specialists in Occupational Medicine (AEEMT), the Spanish Association of Cardiovascular Nursing (AEEC), the Spanish Heart Foundation (FEC), and the Spanish Cancer Association (AECC).


Assuntos
Cardiologia , Doenças Cardiovasculares , Hematologia , Neoplasias , Radioterapia (Especialidade) , Doenças Cardiovasculares/epidemiologia , Doenças Cardiovasculares/etiologia , Doenças Cardiovasculares/terapia , Consenso , Fatores de Risco de Doenças Cardíacas , Humanos , Oncologia , Neoplasias/complicações , Neoplasias/epidemiologia , Neoplasias/terapia , Fatores de Risco
7.
Arch. prev. riesgos labor. (Ed. impr.) ; 24(1): 20-33, ene.-mar. 2021. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-197118

RESUMO

INTRODUCCIÓN: La promoción de la salud en el trabajo integra las iniciativas en salud y seguridad en ámbito ocupacional, con mejoras personales, incremento de productividad y menores riesgos y gastos sociales, especialmente en migraña, como enfermedad neurológica con prevalencia estimada en el 11% de la población. El objetivo de este trabajo fue conocer las condiciones preventivas de los trabajadores con migraña y las opciones de gestión preventiva en sus empresas. MÉTODO: Estudio observacional transversal realizado en 3.342 pacientes de España, Italia, Francia, Portugal, Irlanda, Reino Unido, Alemania y otros países de la UE mediante encuesta anónima en la web de la European Migraine & Headache Alliance (EMHA-web), entre septiembre de 2018 y enero de 2019. RESULTADOS: Estrés laboral y uso de PVD son los riesgos más referidos por los trabajadores con migraña. El 43.71% de trabajadores desconoce el tipo de Servicio de Prevención de su empresa, 49.06% no dispone de servicio médico; el 67.67% no ha tenido impedimentos de acceso laboral por migraña, ni despido o no renovación del contrato, pero el 42,14% tuvo algún conflicto por pérdida de productividad; el 26,54% desconoce el concepto de especial sensibilidad o no lo ha solicitado por migraña; un 55,42% no se ha sentido comprendido ni apoyado por su empresa en sus limitaciones por migraña, pero sí por los compañeros. CONCLUSIÓN: Se observa una deficiente información preventiva y escaso uso de las opciones de gestión adaptativa en las empresas para personas con migraña


INTRODUCTION: Workplace health promotion integrates initiatives in health and safety in the occupational field, with personal improvements, increased productivity and lower risks and social cost, especially with respect to migraine headaches, a neurological disorder affecting approximately 11% of the population. The objective of this study was to know the preventive resources available to workers with migraine headaches and the preventive management options in their companies. METHOD: Cross-sectional observational study of 3,342 patients from Spain, Italy, France, Portugal, Ireland, United Kingdom, Germany and other European Union countries, conducted through an anonymous survey on the web of the European Migraine & Headache Alliance (EMHA-web), from September 2018 to January 2019. RESULTS: Occupational stress (77.65%) and use of computer monitors (63.87%) are the most common risks described by workers with migraine. About. 43.71% of workers are not familiar with the type of occupational health service present in their company, 49.06% do not have a medical service; 67.67% reported no work-related limitations due to migraine, neither dismissal nor non-renewal of their contract (88.29%), but 42.14% had experienced some conflict due to decreased productivity; 26.54% were unaware of the concept of vulnerable workers or had not requested this status because of their migraine (63.8%), nor had they demanded job accommodations (67.64%) or job change (80.89%); 55.42% did not feel understood or supported by their company in their limitations due to migraine, although they did feel they were supported by their colleagues (63.07%). CONCLUSION: We found that preventive resources and information were deficient, and that there was little use of adaptive management options for workers with migraine in their companies


Assuntos
Humanos , Masculino , Feminino , Transtornos de Enxaqueca/prevenção & controle , Serviços de Saúde do Trabalhador/estatística & dados numéricos , Transtornos de Enxaqueca/epidemiologia , Estudos Transversais , Inquéritos Epidemiológicos , Saúde Ocupacional/estatística & dados numéricos , Riscos Ocupacionais , Local de Trabalho , Europa (Continente)/epidemiologia
10.
Lung ; 195(1): 53-57, 2017 02.
Artigo em Inglês | MEDLINE | ID: mdl-27752830

RESUMO

Reports regarding smoking differences in α-klotho expression have provided conflicting results. In the current study we focused on the influence of smoking intensity to serum levels of the aging molecule α-klotho in healthy smokers. 40 middle aged healthy smokers without airway obstruction or restriction were selected for the analysis. Serum levels of soluble α-klotho were significantly higher in heavy smokers (P < 0.001). These results are in agreement with the possibility that α-klotho acts as anti-inflammatory molecule and strengthen the hypothesis that an increase of serum levels of α-klotho might be a compensatory response to smoking stress in healthy population.


Assuntos
Fumar Cigarros/sangue , Glucuronidase/sangue , Produtos do Tabaco/estatística & dados numéricos , Adulto , Fumar Cigarros/fisiopatologia , Volume Expiratório Forçado , Voluntários Saudáveis , Humanos , Proteínas Klotho , Masculino , Pessoa de Meia-Idade , Estresse Oxidativo , Capacidade Vital
11.
Arch. prev. riesgos labor. (Ed. impr.) ; 19(4): 215-221, oct.-dic. 2016. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-156440

RESUMO

Objetivo: El trabajo a bordo de un buque a menudo se realiza lejos de tierra, lo que dificulta el acceso al tratamiento médico adecuado en caso necesario. Si se produce un evento cardiovascular en un tripulante embarcado, la demora en la atención médica puede dar lugar a graves consecuencias para su salud. Por ello se es importante detectar los factores de riesgo cardiovascular (FRCV) en estos trabajadores. El objetivo del trabajo es analizar la frecuencia de los FRCV en los trabajadores del mar en el Servicio de Sanidad Marítima de Madrid. Métodos: Estudio descriptivo realizado en una población de 334 trabajadores en 2011, analizando la frecuencia de los FRCV, por sexo y por edad, la presencia simultánea de FRCV en un mismo sujeto y el riesgo SCORE total de cada individuo. Resultados: La mayoría de los FRCV estudiados presentó una elevada prevalencia, siendo superior en los varones y en los mayores de 45 años, destacando la tensión arterial en cifras de riesgo (40,1%), la hipercolesterolemia (49,7%), el tabaquismo (33,5%), el sobrepeso (44,6%) y la obesidad (17,4%). Conclusiones: Ante la elevada prevalencia de la mayoría de los factores de riesgo cardiovascular en la población de trabajadores del mar la realización del reconocimiento médico previo a embarque debe tratar de identificarlos


Objective: Working at sea makes it difficult to receive proper medical attention. Moreover, the prognosis of an acute cardiovascular event often depends on the measures taken in the first few hours after the onset of symptoms, but are often delayed in seamen. Thus, it is very important to detect cardiovascular risk factors in these workers as early as possible. The aim of this study was to measure the prevalence of cardiovascular risk factors among sailors. Methods: Data were on a sample of 334 individuals in the Madrid Maritime Health Service in 2011. We examined the distribution of cardiovascular risk factors, by age and sex, together withthe presence of various risk factors in the same subject and we calculated the global SCORE risk of each individual. Results: Most cardiovascular risk factors were highly prevalent, more frequent among men and individuals older than 45 years, especially risk blood pressure values (40,1%), hypercholesterolemia (49,7%), tobacco use (33,5%), overweight (44,6%) and obesity (17,4%). Conclusions: Since the prevalence of cardiovascular risk factors among this group of seafarers was high, we consider that pre-voyage medical exams must be very detailed in order to detect cardiovascular risk factors in this population


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Idoso , Doenças Cardiovasculares/epidemiologia , Consentimento Livre e Esclarecido , Exames Médicos , Espanha/epidemiologia , Prevalência , Doenças Cardiovasculares/prevenção & controle , Saúde Ocupacional , Ambiente Marinho , 16054 , Consentimento Livre e Esclarecido/normas
12.
Arch Prev Riesgos Labor ; 19(4): 215-221, 2016.
Artigo em Espanhol | MEDLINE | ID: mdl-27855252

RESUMO

OBJECTIVE: Working at sea makes it difficult to receive proper medical attention. Moreover, the prognosis of an acute cardiovascular event often depends on the measures taken in the first few hours after the onset of symptoms, but are often delayed in seamen. Thus, it is very important to detect cardiovascular risk factors in these workers as early as possible. The aim of this study was to measure the prevalence of cardiovascular risk factors among sailors. METHODS: Data were on a sample of 334 individuals in the Madrid Maritime Health Service in 2011. We examined the distribution of cardiovascular risk factors, by age and sex, together withthe presence of various risk factors in the same subject and we calculated the global SCORE risk of each individual. RESULTS: Most cardiovascular risk factors were highly prevalent, more frequent among men and individuals older than 45 years, especially risk blood pressure values (40,1%), hypercholesterolemia (49,7%), tobacco use (33,5%), overweight (44,6%) and obesity (17,4%). CONCLUSIONS: Since the prevalence of cardiovascular risk factors among this group of seafarers was high, we consider that pre-voyage medical exams must be very detailed in order to detect cardiovascular risk factors in this population.


El trabajo a bordo de un buque a menudo se realiza lejos de tierra, lo que dificulta el acceso al tratamiento médico adecuado en caso necesario. Si se produce un evento cardiovascular en un tripulante embarcado, la demora en la atención médica puede dar lugar a graves consecuencias para su salud. Por ello se es importante detectar los factores de riesgo cardiovascular (FRCV) en estos trabajadores. El objetivo del trabajo es analizar la frecuencia de los FRCV en los trabajadores del mar en el Servicio de Sanidad Marítima de Madrid. MÉTODOS: Estudio descriptivo realizado en una población de 334 trabajadores en 2011, analizando la frecuencia de los FRCV, por sexo y por edad, la presencia simultánea de FRCV en un mismo sujeto y el riesgo SCORE total de cada individuo.

13.
Int J Mol Sci ; 17(10)2016 Oct 14.
Artigo em Inglês | MEDLINE | ID: mdl-27754415

RESUMO

INTRODUCTION: Tobacco smoke contains many potentially harmful compounds that may act differently and at different stages in breast cancer development. The focus of this work was to assess the possible role of cigarette smoking (status, dose, duration or age at initiation) and polymorphisms in genes coding for enzymes involved in tobacco carcinogen metabolism (CYP1A1, CYP2A6) or in DNA repair (XRCC1, APEX1, XRCC3 and XPD) in breast cancer development. METHODS: We designed a case control study with 297 patients, 217 histologically verified breast cancers (141 smokers and 76 non-smokers) and 80 healthy smokers in a cohort of Spanish women. RESULTS: We found an association between smoking status and early age at diagnosis of breast cancer. Among smokers, invasive carcinoma subtype incidence increased with intensity and duration of smoking (all Ptrend < 0.05). When smokers were stratified by smoking duration, we only observed differences in long-term smokers, and the CYP1A1 Ile462Ile genotype was associated with increased risk of breast cancer (OR = 7.12 (1.98-25.59)). CONCLUSIONS: Our results support the main effect of CYP1A1 in estrogenic metabolism rather than in tobacco carcinogen activation in breast cancer patients and also confirmed the hypothesis that CYP1A1 Ile462Val, in association with long periods of active smoking, could be a breast cancer risk factor.


Assuntos
Neoplasias da Mama/etiologia , Neoplasias da Mama/genética , Polimorfismo Genético , Fumar/efeitos adversos , Fumar/genética , Adulto , Idoso , Mama/metabolismo , Mama/patologia , Neoplasias da Mama/diagnóstico , Estudos de Casos e Controles , Citocromo P-450 CYP1A1/genética , Citocromo P-450 CYP2A6/genética , DNA Liase (Sítios Apurínicos ou Apirimidínicos)/genética , Proteínas de Ligação a DNA/genética , Feminino , Predisposição Genética para Doença , Humanos , Pessoa de Meia-Idade , Proteína 1 Complementadora Cruzada de Reparo de Raio-X , Proteína Grupo D do Xeroderma Pigmentoso/genética
14.
Rev. Asoc. Esp. Espec. Med. Trab ; 25(3): 166-175, sept. 2016. tab
Artigo em Espanhol | IBECS | ID: ibc-157374

RESUMO

Objetivo: estudiar la prevalencia del hábito tabáquico en trabajadores del mar entre 2009 y 2015. Material y método: estudio descriptivo transversal de los datos informatizados de los reconocimientos médicos previos a embarque (RMPE) en los años 2009-2015 en los que se analizó la frecuencia del hábito tabáquico en la población total, así como por sexo, edad (< y ≥ 45 años) y puesto de trabajo (oficiales y no oficiales). Resultados: el tabaquismo resultó más prevalente en los varones, en los sujetos menores de 45 años (con significación estadística en 2014) y en los no oficiales (estadísticamente significativo en 2009 y 2011). Conclusiones: se observó una tendencia a la disminución del hábito tabáquico en los años estudiados, que fue superior a la de la población general española, tal vez por el efecto de las recomendaciones dadas durante los reconocimientos médicos laborales, por lo que recomendamos seguir dándolas durante los RMPE (AU)


Objective: The aim of this work was to determine the prevalence of smoke habit in a group of seafarers in the years 2009-2015. Methods: Data obtained of the pre-embarkation medical checkups files finished between January 1st and December 31st of each year were included. Smoke habit’s prevalence was determined in the subjects studied, also by sex, age (< y ≥ 45 years) and job (officers and no officers). Results: Smoking was more prevalent among men, younger than 45 (statistically significant in 2014) and among no officers (significant in 2009 and 2011). Conclusions: We observed a trend to diminish smoke habit along the studied years, higher than in Spanish general population, perhaps due to the beneficial effects of the recommendations given during the medical pre-embarkation checkup to diminish smoking in the studied subjects, so we recommend giving medical advice during pre-embarkation medical examinations (AU)


Assuntos
Humanos , Tabagismo/epidemiologia , Fumar/epidemiologia , Distribuição por Idade e Sexo , Avaliação de Eficácia-Efetividade de Intervenções , Navios
15.
Rev. Asoc. Esp. Espec. Med. Trab ; 25(3): 176-183, sept. 2016. graf
Artigo em Espanhol | IBECS | ID: ibc-157375

RESUMO

El avance del conocimiento científico incorpora nuevas tecnologías y también nuevos conceptos. En toxicología medioambiental y laboral se ha acuñado en los últimos años un nuevo término, exposoma, que agrupa todas las exposiciones ambientales a las que el ser humano está sometido desde la concepción en adelante. Surge como una nueva estrategia para evidenciar los factores de riesgo de enfermedades generadas por el medio ambiente. Supone un reto al investigador en muchos aspectos, especialmente en cuanto a la evaluación del riesgo por exposición, puesto que han de ser considerados varios cientos de exposiciones variables en el tiempo y también desafíos estadísticos, ya que los métodos existentes actualmente no pueden separar de una forma clara las exposiciones que verdaderamente afectan a la salud y las exposiciones correlacionadas. Se revisan aquí algunas de las principales publicaciones en torno a este tema de los últimos años, su enfoque en Salud Ocupacional y repercusión en Salud Pública (AU)


Advancement of scientific knowledge incorporates new technologies and new concepts as well. In Environmental and Occupational Toxicology has been incorporated in the last years a new term, exposome, encompassing all environmental exposures from conception onwards. It arises as a new strategy to evidence environmental disease risk factors and supposes a research challenge on many related aspects, especially with regard to the evaluation of the risk from exposure, that several hundreds of time-varying exposures need to be considered and Statistical Challenges, as currently existing statistical methods cannot efficiently untangle the exposures truly affecting the health outcome from correlated exposures. We review here some of the major publications on this topic in recent years, its focus on Occupational Health and impact on Public Health (AU)


Assuntos
Humanos , Exposição Ocupacional/análise , Exposição Ambiental/análise , Saúde Ocupacional/tendências , Serviços de Saúde do Trabalhador/estatística & dados numéricos , Poluentes Ocupacionais do Ar/análise , Poluição Ambiental/análise , Toxicidade/análise
16.
Int Marit Health ; 67(1): 3-8, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27029922

RESUMO

BACKGROUND AND AIM: There is a high prevalence in the Spanish general population of some cardiovascular risk factors like overweight, obesity and hypercholesterolaemia. But there is lack of research on Spanish seafarers. On the other hand, there is strong evidence of the cardiovascular risk predictive value of some biomarkers. The purpose of this work was to study the convenience of the introduction of detailed diet questionnaires and the measurement of some biomarkers in the pre-embarkation medical examination. MATERIALS AND METHODS: Seafarers undergoing medical checkup during 2011 in Madrid, Spain (n = 334). Overweight and obese subjects received general advice on healthy diet and physical activity. Seventy-four of them were followed up in 2012 and 2013. Glycated haemoglobin (HbA1c), high-sensitivity C-reactive protein (hs-CRP), thyrotropin (TSH) and microalbuminuria were measured in two selected groups of patients in 2011. RESULTS: Overweight and obesity were present in 207 (62%) individuals of the studied population. Those followed up in 2012 and 2013 showed a reduction of body mass index, waist circumference and total cholesterol values. We observed risk value of HbA1c in 60 (35.5%) individuals with significant association to other cardiovascular risk factors. Microalbuminuria appeared in subjects with high blood pressure. High TSH and hs-CRP were not significantly present in our population. CONCLUSIONS: 1. Measurement of HbA1c during medical checkups improves early detection of cardiovascular risk in seafarers. 2. Individuals with overweight and obesity responded positively to medical advice and diminished their risk factors, thus it may be more effective to introduce detailed questionnaires on this issue.


Assuntos
Doenças Cardiovasculares/prevenção & controle , Promoção da Saúde/métodos , Doenças Profissionais/prevenção & controle , Serviços de Saúde do Trabalhador/métodos , Exame Físico/métodos , Adolescente , Adulto , Idoso , Biomarcadores/sangue , Doenças Cardiovasculares/sangue , Doenças Cardiovasculares/diagnóstico , Doenças Cardiovasculares/etiologia , Feminino , Seguimentos , Hemoglobinas Glicadas/metabolismo , Humanos , Masculino , Pessoa de Meia-Idade , Medicina Naval , Doenças Profissionais/sangue , Doenças Profissionais/diagnóstico , Doenças Profissionais/etiologia , Sobrepeso/complicações , Sobrepeso/diagnóstico , Sobrepeso/terapia , Medição de Risco , Fatores de Risco , Espanha , Adulto Jovem
17.
Nicotine Tob Res ; 18(4): 447-52, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25987675

RESUMO

INTRODUCTION: Smoking implies exposure to carcinogenic agents that causes DNA damage, which could be suspected to enhance telomere attrition. To protect and deal with DNA damage, cells possess mechanisms that repair and neutralize harmful substances. Polymorphisms altering DNA repair capacity or carcinogen metabolism may lead to synergistic effects with tobacco carcinogen-induced shorter telomere length independently of cancer interaction. The aim of this study was to explore the association between leukocyte telomere length (LTL) and several genetic polymorphisms in DNA repair genes and carcinogen metabolizers in a cohort of healthy smokers. METHODS: We evaluated the effect of six genetic polymorphisms in cytochrome P1A1 (Ile462Val), XRCC1 (Arg399Gln), APEX1 (Asp148Glu), XRCC3 (Thr241Met), and XPD (Asp312Asn; Lys751Gln) on LTL in a cohort of 145 healthy smokers in addition to smoking habits. RESULTS: Logistic regression analysis showed an association between XRCC1 399Gln allele and shorter telomere length (OR = 5.03, 95% CI = 1.08% to 23.36%). There were not association between the rest of polymorphisms analyzed and LTL. CONCLUSIONS: Continuous exposure to tobacco could overwhelm the DNA repair machinery, making the effect of the polymorphisms that reduce repair capacity more pronounced. Analyzing the function of smoking-induced DNA-repair genes and LTL is an important goal in order to identify therapeutic targets to treat smoking-induced diseases.


Assuntos
Carcinógenos/metabolismo , Reparo do DNA/genética , Proteínas de Ligação a DNA/genética , Leucócitos/fisiologia , Polimorfismo Genético/genética , Fumar/genética , Telômero/genética , População Branca/genética , Adulto , Idoso , Alelos , Estudos de Coortes , Humanos , Pessoa de Meia-Idade , Fumar/epidemiologia , Espanha/epidemiologia , Proteína 1 Complementadora Cruzada de Reparo de Raio-X
18.
Arch. prev. riesgos labor. (Ed. impr.) ; 18(4): 185-191, oct.-dic. 2015.
Artigo em Espanhol | IBECS | ID: ibc-146637

RESUMO

Objetivos: Describir las lesiones por accidentes de trabajo (LAT) relacionados con el tráfico (LATT) ocurridas en los trabajadores de una entidad bancaria desde 2007 a 2013 en España. Adicionalmente, describir las características de las LATT en función de sexo y edad de los accidentados, así como la ocurrencia de bajas médicas en relación con este tipo de lesiones. Métodos: Estudio transversal descriptivo del registro de LAT mantenido por el servicio de prevención de la empresa estudiada. Se describen las frecuencias absolutas (n) y relativas (%) en relación con las características de interés. Para las comparaciones se utiliza el test chi cuadrado. Resultados: En una plantilla total de 14.541 trabajadores, en el periodo de estudio se registraron 1.517 LAT. El 27% de estas LAT fueron LATT. El 1,3% de las LATT fueron considerados graves o mortales. Se observan relaciones significativas (p<0,05) con el sexo y la edad. Las lesiones en copilotos, las LATT 'in itinere' y el diagnóstico 'esguinces/torceduras' son más frecuentes en las mujeres. Las LATT 'en desplazamiento' y el diagnóstico'fracturas cerradas' son más frecuentes en los hombres. También es más frecuente la situación de baja médica en caso de LATT en comparación con las LAT. Conclusiones: La frecuencia de LATT sobre el total de LAT en la muestra estudiada es casi tres veces mayor que en la población laboral general española, aunque en nuestro estudio las LATT graves son menos frecuentes. Las LATT presentan diferencias en su distribución según edad y sexo de los trabajadores, y también se asocian con mayor frecuencia a baja médica en comparación con el conjunto de las LAT. La salud pública y la medicina del trabajo deben buscar estrategias para controlar este tipo de lesiones


Objective: To study physical harm caused by road accidents (LATT in Spanish) among employees of a Spanish financial institution from 2007 to 2013. Additionally, we tried to define damage features in each sex and at different ages in hurt patients, as well as work disability caused by this type of injury. Methods: Cross-sectional study of labor injuries verified by the occupational medical service of the bank. Absolute (n) and relative (%) frequencies related to interesting variables were described. Chi-square test was used to assess correlation. Results: Along the mentioned period of time, 1.517 traumatic occupational injuries were recorded on a population of 14.541 workers. 27% of them were LATT. 1,3% of these were fatal or seriously harmful, significantly associated to sex and age (p< 0,05). Co-driver damage, LATT in itinere and twist or sprain were more common in women. LATT at work and closed fractures were more frequent in men.Work disability caused by LATT was higher than other traumatic occupational injuries. Conclusions: LATT in the studied sample were almost three times higher than LATT are among general Spanish population, but serious lesions in our group were less common.We observed differences in LATT distribution by sexes and ages in workers included in this study, and also a higher incidence of work disability compared to the whole traumatic occupational injuries. Public health and occupational health authorities must find efficient strategies in order to diminish the incidence of these LATT-associated injuries


Assuntos
Adulto , Feminino , Humanos , Masculino , Acidentes de Trânsito/estatística & dados numéricos , /estatística & dados numéricos , Traumatismos Ocupacionais/epidemiologia , /prevenção & controle , Riscos Ocupacionais , Vigilância Sanitária/normas , Estudos Transversais/métodos , Medicina do Trabalho/métodos , Medicina do Trabalho/tendências
19.
Med. clín (Ed. impr.) ; 145(8): 338-340, oct. 2015. tab
Artigo em Espanhol | IBECS | ID: ibc-144606

RESUMO

Objetivos: El objetivo de este estudio es examinar la relación entre lipoatrofia semicircular (LS), marcadores de inflamación (proteína C reactiva ultrasensible, [PCRus]), adipocinas (leptina, quemerina y vaspina) y marcadores inmunitarios (factor reumatoide [FR], fracciones de complemento C3 y C4, anticuerpos antinucleares [ANA], HLA DR3 y DR4). La quemerina es una adipocina, pero también es un marcador de inmunidad. Métodos: Estudio de casos y controles realizado en mayo de 2013. Participaron 21 casos, y como control participó el empleado sano más cercano a cada caso. Se utilizaron test no paramétricos (Kruskal-Wallis). Resultados: Se observó una relación estadísticamente significativa (p < 0,05) entre LS y niveles séricos de PCRus elevados, de leptina elevados y de quemerina disminuidos. Conclusiones: i) Parece haber un componente inflamatorio subyacente (PCRus elevada) en la LS; ii) la alteración de las adipocinas (leptina elevada y quemerina disminuida) apoyan la teoría de que la diferenciación adipocítica esté afectada en la LS, y iii) no hemos encontrado ningún marcador inmunitario (FR, etc.) asociado con LS, excepto la misma quemerina, que podría explicar una posible asociación entre LS y autoinmunidad (AU)


Objectives: The aim of this study was to examine the relationship between semicircular lipoatrophy (SL), inflammation marker (high sensibility C-reactive protein [hs-CRP]), adipokines (leptine, chemerine and vaspine) and autoimmune markers (rheumatoid factor [RF], C3 and C4 complement fractions, antinuclear antibodies [ANA], HLA DR3, and DR4). Chemerine is an adipokine, but also is an immunity marker. Methods: A case-control study was performed in May 2013; 21 cases were included. The closest healthy coworker to each case was used as a control. We calculated Kruskal-Wallis nonparametric test. Results: We found statistical significance (P < .05) between SL and raised hs-CRP, raised leptine and low chemerine. Conclusions: i) There seems to be an underlying inflammatory component (raised hs-CRP) in SL; ii) adipokine alteration (raised leptine and low chemerine) supports the idea that adipocytic differentiation is affected in SL, and iii) we have not found any immune marker associated with SL, except chemerine itself, which could explain a possible association between SL and immunity (AU)


Assuntos
Feminino , Humanos , Masculino , Transtornos Musculares Atróficos/complicações , Transtornos Musculares Atróficos/diagnóstico , Transtornos Musculares Atróficos/fisiopatologia , Adipocinas/biossíntese , Adipocinas , Inflamação/diagnóstico , Anticorpos Antinucleares , Fator Reumatoide , Atrofia Muscular/complicações , Atrofia Muscular/diagnóstico , Estudos de Casos e Controles , Inquéritos e Questionários , Índice de Massa Corporal , Proteína C-Reativa
20.
Arch. prev. riesgos labor. (Ed. impr.) ; 18(3): 130-135, jul.-sept. 2015. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-139596

RESUMO

Objetivos: Describir la distribución de la incidencia y duración de la incapacidad temporal por contingencia común (ITcc), en el periodo comprendido entre enero y diciembre de 2013, por grupo diagnóstico, en una empresa del sector bancario. Métodos: Estudio transversal descriptivo sobre una población que mostró 3.193 eventos que han conllevado ITcc de ≥1 día por motivo médico, distinto al accidente de trabajo o enfermedad profesional. Se examinó la distribución de los episodios por el diagnóstico médico, según la duración mediana, los percentiles 25 y 75, la media y la desviación estándar. Resultados: La duración mediana fue de 9 días para aquellos casos en los que se obtuvo un diagnóstico clínico (n=2.931, 91,8%); los percentiles 25 y 75 fueron de 4 y 32 días, respectivamente. Las patologías más frecuentes fueron las respiratorias (19,9%), las traumatológicas (19,1%), y las relacionadas con el embarazo (17,3%). Las neoplasias presentaron la mayor duración mediana (49 días), seguidas por las relacionadas con el embarazo (39 días) y las psiquiátricas (23 días). Conclusiones: La incidencia acumulada anual de ITcc en la muestra estudiada fue menor que la observada en estudios similares, pero la duración de los episodios en nuestra muestra fue mayor. Incidencia y duración por grupos diagnósticos son muy similares a la descrita en la bibliografía, excepto las relacionadas con el embarazo que son claramente superiores (incidencia de 4 a 11 veces y duración 0,4 veces) en la empresa estudiada (p<0,001). El seguimiento de la ITcc es útil desde el punto de vista preventivo, en la empresa estudiada sugieren la necesidad de priorizar el estudio de las exposiciones laborales que puedan repercutir en la salud de las trabajadoras embarazadas


Objectives: To describe the incidence and duration of episodes of non work-related temporary sickness absence (SA) between January and December of 2013, by diagnostic groups, in a banking sector Company. Methods: Cross-sectional study of 3.193 episodes of SA (≥1 day), excluding work-related injuries and illnesses. The distribution of the duration of SA episodes by medical diagnosis was analyzed by calculating the median duration, 25th and 75th percentiles, mean and standard deviation. Results: The median duration of SA was 9 days for cases where there was a medical diagnosis (n=2.931, 91.8%); the 25th and 75th percentiles were 4 and 32 days, respectively. The most frequent pathologies were respiratory (19.9%), followed by musculoskeletal (19.1%) and pregnancy-related disorders (17.3%). Neoplasms had the longest median duration (49 days), followed by pregnancy-related disorders (39 days) and psychiatric disorders (23 days). Conclusions: Overall sickness absence incidence in our study population was lower, but had a longer duration, as compared to similar studies. The incidence and duration by diagnostic groups were very similar to that reported in the literature, except for pregnancy-related disorders, where both were clearly higher (incidence 4 to 11 times and duration 0.4 times larger) in our company (p<0,001). This analysis is useful from a prevention perspective, and suggests the need to prioritize the study to the control of potential workplace exposures that might be affecting pregnant workers' health


Assuntos
Humanos , Licença Médica/estatística & dados numéricos , Absenteísmo , Grupos Diagnósticos Relacionados/estatística & dados numéricos , Estudos Transversais , Serviços de Saúde do Trabalhador/estatística & dados numéricos , Doenças Profissionais/epidemiologia , Complicações na Gravidez/epidemiologia
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